Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation.
To determine whether the transcription regulatory activities of the adenoviral E1a gene play a role in its ability to transform primary cells we have constructed an extensive series of mutations within the E1a gene. The mutants have been characterized for their ability to transactivate the adenovira...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1987
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