The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.

BACKGROUND: The microsomal triglyceride transfer protein (MTP) transfers lipids into apolipoprotein B-containing lipoproteins for secretion from liver, intestine, and heart. The T-variant of a functional polymorphism in the MTP promoter, MTP-493G/T, has been associated with reduced low-density lipo...

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Bibliographic Details
Main Authors: Ledmyr, H, McMahon, A, Ehrenborg, E, Nielsen, L, Neville, M, Lithell, H, MacFarlane, P, Packard, C, Karpe, F
Format: Journal article
Language:English
Published: 2004