Action of incretins on the pancreatic alpha cell
T2D is a bihormonal disorder characterised by hypoinsulinaemia and hyperglucagonaemia. The incretin GLP-1 is therapeutically attractive as, in addition to augmenting glucose-stimulated insulin secretion, it is also able to suppress glucagon secretion from alpha cells. However, the mechanism by whi...
| Main Authors: | , , , , |
|---|---|
| Format: | Book section |
| Published: |
Imperial College Press
2015
|