Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks that allow causal inference. Here, we discuss the characteristics of Recall-...

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Bibliographic Details
Main Authors: Corbin, LJ, Tan, VY, Hughes, DA, Wade, KH, Paul, DS, Tansey, KE, Butcher, F, Dudbridge, F, Howson, JM, Jallow, MW, John, C, Kingston, N, Lindgren, CM, O'Donavan, M, O'Rahilly, S, Owen, MJ, Palmer, CNA, Pearson, ER, Scott, RA, DA van Heel, Whittaker, J, Frayling, T, Tobin, MD, Wain, LV, Smith, GD, Evans, DM, Karpe, F, McCarthy, MI, Danesh, J, Franks, PW, Timpson, NJ
Format: Journal article
Language:English
Published: Nature Publishing Group 2018