FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer.
OBJECTIVE: We have shown previously that cutting or loading articular cartilage resulted in a fibroblast growth factor-2 (FGF-2) dependent activation of the extracellularly regulated kinase (ERK), and induction of a number of chondrocyte regulatory proteins including tissue inhibitor of metalloprote...
Κύριοι συγγραφείς: | Vincent, T, McLean, C, Full, L, Peston, D, Saklatvala, J |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2007
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
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Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
ανά: McLean, C, κ.ά.
Έκδοση: (2010) -
Basic fibroblast growth factor: An extracellular mechanotransducer in articular cartilage?
ανά: Vincent, T, κ.ά.
Έκδοση: (2006) -
Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
ανά: Vincent, T, κ.ά.
Έκδοση: (2006) -
Modulation of Perlecan Protein towards Chondrocyte Secretion Factors at the Articular Cartilage in Hyperglycemic Animal Model
ανά: Ibrahim Njoto, κ.ά.
Έκδοση: (2019-04-01)