A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis.

Interleukin (IL)-1α is a potent proinflammatory cytokine that has been implicated in the development of atherosclerosis. We investigated whether a vaccine inducing IL-1α neutralizing antibodies could interfere with disease progression in a murine model of atherosclerosis. We immunized Apolipoprothin...

Full description

Bibliographic Details
Main Authors: Tissot, A, Spohn, G, Jennings, G, Shamshiev, A, Kurrer, M, Windak, R, Meier, M, Viesti, M, Hersberger, M, Kündig, T, Ricci, R, Bachmann, M
Format: Journal article
Language:English
Published: 2013