Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer

Genomic instability is a hallmark of cancer, and has a central role in the initiation and development of breast cancer1,2. The success of poly-ADP ribose polymerase inhibitors in the treatment of breast cancers that are deficient in homologous recombination exemplifies the utility of synthetically l...

Full description

Bibliographic Details
Main Authors: Yeow, ZY, Lambrus, B, Marlow, R, Zhan, K, Durin, M-A, Evans, L, Scott, P, Phan, T, Park, E, Ruiz, L, Moralli, D, Knight, E, Badder, L, Novo, D, Haider, S, Green, C, Tutt, A, Lord, C, Chapman, J, Holland, A
Format: Journal article
Language:English
Published: Springer Nature 2020