Correlating glycoforms of DC-SIGN with stability using a combination of enzymatic digestion and ion mobility mass spectrometry

The immune scavenger protein DC‐SIGN interacts with glycosylated proteins and has a putative role in facilitating viral infection. How these recognition events take place with different viruses is not clear and the effects of glycosylation on the folding and stability of DC‐SIGN have not been report...

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Autors principals: Yen, HY, Liko, I, Gault, J, Wu, D, Struwe, WB, Robinson, CV
Format: Journal article
Idioma:English
Publicat: Wiley 2020