Opportunities for improving the efficiency of paediatric HIV treatment programmes.

Opportunities for improving the efficiency of paediatric HIV treatment programmes.

<strong>Objectives:</strong> To conduct two economic analyses addressing whether to: routinely monitor HIV-infected children on antiretroviral therapy (ART) clinically or with laboratory tests; continue or stop cotrimoxazole prophylaxis when children become stabilized on ART. <strong&...

Bibliografski detalji
Glavni autori:	Revill, P, Walker, S, Mabugu, T, Nathoo, K, Mugyenyi, P, Kekitinwa, A, Munderi, P, Bwakura-Dangarembizi, M, Musiime, V, Bakeera-Kitaka, S, Nahirya-Ntege, P, Walker, A, Sculpher, M, Gibb, D
Format:	Journal article
Jezik:	English
Izdano:	Lippincott, Williams and Wilkins 2015

Slični predmeti

Tuberculosis incidence is high in HIV-infected African children but is reduced by co-trimoxazole and time on antiretroviral therapy.
od: Crook, A, i dr.
Izdano: (2016)

A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa.
od: Bwakura-Dangarembizi, M, i dr.
Izdano: (2014)

Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial.
od: Kekitiinwa, A, i dr.
Izdano: (2013)

Pubertal development in HIV-infected African children on first-line antiretroviral therapy.
od: Szubert, A, i dr.
Izdano: (2015)

Prevalence of lipodystrophy and metabolic abnormalities in HIV-infected African children after 3 years on first-line antiretroviral therapy.
od: Bwakura-Dangarembizi, M, i dr.
Izdano: (2015)

Mortality in the year following antiretroviral therapy initiation in HIV-infected adults and children in Uganda and Zimbabwe.
od: Walker, A, i dr.
Izdano: (2012)

Pharmacokinetics of zidovudine dosed twice daily according to World Health Organization weight bands in Ugandan HIV-infected children.
od: Fillekes, Q, i dr.
Izdano: (2014)

Single-dose nevirapine exposure does not affect response to antiretroviral therapy in HIV-infected African children aged below 3 years.
od: Musoke, P, i dr.
Izdano: (2015)

Inflammatory biomarkers in HIV-infected children hospitalized for severe malnutrition in Uganda and Zimbabwe
od: Prendergast, A, i dr.
Izdano: (2019)

Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial
od: Szubert, A, i dr.
Izdano: (2017)

Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1.
od: Kasirye, P, i dr.
Izdano: (2012)

The cost-effectiveness of prophylaxis strategies for individuals with advanced HIV starting treatment in Africa
od: Walker, SM, i dr.
Izdano: (2020)

Reduced bacterial skin infections in HIV-infected African children randomized to long-term cotrimoxazole prophylaxis
od: Prendergast, A, i dr.
Izdano: (2016)

Predicting patterns of long-term CD4 reconstitution in HIV-infected children starting antiretroviral therapy in sub-Saharan Africa: a cohort-based modelling study.
od: Picat, M, i dr.
Izdano: (2013)

DART and laboratory monitoring of HIV treatment Reply
od: Walker, A, i dr.
Izdano: (2010)

Pharmacokinetics and acceptability of once- versus twice-daily lamivudine and abacavir in HIV type-1-infected Ugandan children in the ARROW Trial.
od: Musiime, V, i dr.
Izdano: (2010)

Marginal structural models for repeated measures where intercept and slope are correlated: an application exploring the benefit of nutritional supplements on weight gain in HIV-infected children initiating antiretroviral therapy
od: Farmer, R, i dr.
Izdano: (2020)

Baseline inflammatory biomarkers identify subgroups of HIV-infected African children with differing responses to antiretroviral therapy
od: Prendergast, A, i dr.
Izdano: (2016)

Enhanced prophylaxis with antiretroviral therapy for advanced HIV in Africa
od: Hakim, J, i dr.
Izdano: (2017)

Virologic response to first-line efavirenz- or nevirapine-based anti-retroviral therapy in HIV-infected African children
od: Kekitiinwa, A, i dr.
Izdano: (2017)

The impact of viraemia on inflammatory biomarkers and CD4 cell subpopulations in HIV-infected children in sub-Saharan Africa
od: Prendergast, AJ, i dr.
Izdano: (2021)

Virologic response to first-line efavirenz- or nevirapine-based antiretroviral therapy in HIV-infected African children
od: Kekitiinwa, A, i dr.
Izdano: (2017)

Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial.
od: Alexander J Szubert, i dr.
Izdano: (2017-11-01)

Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy.
od: Kikaire, B, i dr.
Izdano: (2007)

Utilization of “prevention of mother-to-child transmission” of HIV services by adolescent and young mothers in Mulago Hospital, Uganda
od: Mariama Mustapha, i dr.
Izdano: (2018-11-01)

Marginal structural models for repeated measures where intercept and slope are correlated: An application exploring the benefit of nutritional supplements on weight gain in HIV-infected children initiating antiretroviral therapy.
od: Ruth E Farmer, i dr.
Izdano: (2020-01-01)

Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.
od: Munderi, P, i dr.
Izdano: (2010)

Effect of handrubbing using locally-manufactured alcohol-based handrubs in paediatric wards in Harare, Zimbabwe
od: Muchaneta Gudza-Mugabe, i dr.
Izdano: (2017-01-01)

A single CD4 test with 250 cells/mm3 threshold predicts viral suppression in HIV-infected adults failing first-line therapy by clinical criteria
od: Gilks, C, i dr.
Izdano: (2013)

Biomarkers of mortality in adults and adolescents with advanced HIV in sub-Saharan Africa
od: Riitho, V, i dr.
Izdano: (2024)

Defeating Paediatric Tuberculous Meningitis: Applying the WHO “Defeating Meningitis by 2030: Global Roadmap”
od: Robindra Basu Roy, i dr.
Izdano: (2021-04-01)

Once- versus twice-daily abacavir and lamivudine in African children: the randomised controlled ARROW Trial
od: Musiime, V, i dr.
Izdano: (2016)

Severe renal dysfunction and risk factors associated with renal impairment in HIV-infected adults in Africa initiating antiretroviral therapy.
od: Reid, A, i dr.
Izdano: (2008)

Ethical and legal constraints to children’s participation in research in Zimbabwe: experiences from the multicenter pediatric HIV ARROW trial
od: Bwakura-Dangarembizi Mutsa, i dr.
Izdano: (2012-07-01)

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial
od: Mallewa, J, i dr.
Izdano: (2018)

Late presentation with HIV in Africa: phenotypes, risk and risk stratification in the REALITY trial
od: Siika, A, i dr.
Izdano: (2018)

Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort.
od: Walker, A, i dr.
Izdano: (2010)

Response to highly active antiretroviral therapy varies with age: the UK and Ireland Collaborative HIV Paediatric Study.
od: Walker, A, i dr.
Izdano: (2004)

Paediatric surgery in Uganda: current challenges and opportunities
od: Alberti, P, i dr.
Izdano: (2024)

Pediatric underdosing of efavirenz: a pharmacokinetic study in Uganda.
od: Fillekes, Q, i dr.
Izdano: (2011)