Molecular dynamics simulations of the dimerization of transmembrane alpha-helices.

Membrane proteins account for nearly a quarter of all genes, but their structure and function remain incompletely understood. Most membrane proteins have transmembrane (TM) domains made up of bundles of hydrophobic alpha-helices. The lateral association of TM helices within the lipid bilayer is a ke...

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Bibliographic Details
Main Authors: Psachoulia, E, Marshall, D, Sansom, MS
Format: Journal article
Language:English
Published: 2010