An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells
The oxygen transport function of hemoglobin (HB) is thought to have arisen ∼500 million years ago, roughly coinciding with the divergence between jawless (Agnatha) and jawed (Gnathostomata) vertebrates. Intriguingly, extant HBs of jawless and jawed vertebrates were shown to have evolved twice, and i...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society of Hematology
2020
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Subjects: |