Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease
<p><strong>Background:</strong> Haploinsufficiency in the Gaucher disease <i>GBA</i> gene, which encodes the lysosomal glucocerebrosidase GBA, and ageing represent major risk factors for developing Parkinson’s disease (PD). Recently, more than fifty other lysosomal stor...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2019
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