Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation.

BACKGROUND: The majority of human embryos created using in vitro fertilisation (IVF) techniques are aneuploid. Comprehensive chromosome screening methods, applicable to single cells biopsied from preimplantation embryos, allow reliable identification and transfer of euploid embryos. Recently, random...

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Bibliographic Details
Main Authors: Wells, D, Kaur, K, Grifo, J, Glassner, M, Taylor, J, Fragouli, E, Munne, S
Format: Journal article
Language:English
Published: BMJ Publishing Group 2014