McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation

In Gram-positive bacteria, the McsB protein arginine kinase is central to protein quality control, labeling aberrant molecules for degradation by the ClpCP protease. Despite its importance for stress response and pathogenicity, it is still elusive how the bacterial degradation labeling is regulated....

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Bibliographic Details
Main Authors: Hajdusits, B, Suskiewicz, MJ, Hundt, N, Meinhart, A, Kurzbauer, R, Leodolter, J, Kukura, P, Clausen, T
Format: Journal article
Language:English
Published: eLife Sciences Publications 2021