Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.

Apicomplexan parasites invade host cells and immediately initiate cell division. The extracellular parasite discharges transmembrane proteins onto its surface to mediate motility and invasion. These are shed by intramembrane cleavage, a process associated with invasion but otherwise poorly understoo...

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Bibliographic Details
Main Authors: Santos, J, Ferguson, D, Blackman, M, Soldati-Favre, D
Format: Journal article
Language:English
Published: 2011