A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy

Infectious agents contribute significantly to the global burden of diseases through both acute infection and their chronic sequelae. We leveraged the UK Biobank to identify genetic loci that influence humoral immune response to multiple infections. From 45 genome-wide association studies in 9,611 pa...

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Bibliografische gegevens
Hoofdauteurs: Chong, AY, Brenner, N, Jimenez-Kaufmann, A, Cortes, A, Hill, M, Littlejohns, TJ, Gilchrist, JJ, Fairfax, BP, Knight, JC, Hodel, F, Fellay, J, McVean, G, Moreno-Estrada, A, Waterboer, T, Hill, AVS, Mentzer, AJ
Formaat: Journal article
Taal:English
Gepubliceerd in: Cell Press 2024