Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: formation of benzo-fused nitrogen heterocycles.

Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: formation of benzo-fused nitrogen heterocycles.

Visa andra versioner (1)

p-Iodophenol and its O-MOM-protected ether can be converted into iodoamines 2. These give cross-conjugated ketones 3 on oxidation with hypervalent iodides in the presence of methanol, and the ketones undergo radical cyclization. Exposure of the products to acid or sequential treatment with a Grignar...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Fletcher, S, Clive, D, Peng, J, Wingert, D
Materialtyp:	Journal article
Språk:	English
Publicerad:	2005

Liknande verk

Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: Formation of benzo-fused nitrogen heterocycles
av: Fletcher, S, et al.
Publicerad: (2005)

Synthesis of diverse 2,3-dihydroindoles, 1,2,3,4-tetrahydroquinolines, and benzo-fused azepines by formal radical cyclization onto aromatic rings.
av: Clive, D, et al.
Publicerad: (2008)

Synthesis of (+)-nocardione A--use of formal radical cyclization onto a benzene ring.
av: Clive, D, et al.
Publicerad: (2003)

Synthesis of (+)-nocardione A--use of formal radical cyclization onto a benzene ring.
av: Clive, D, et al.
Publicerad: (2003)

Formal radical cyclization onto benzene rings--a general method proceeding via cross-conjugated dienones.
av: Clive, D, et al.
Publicerad: (2003)

Formal radical cyclization onto benzene rings: a general method and its use in the synthesis of ent-nocardione A.
av: Clive, D, et al.
Publicerad: (2004)

Ring Transformation of Cyclopropenes to Benzo‐Fused Five‐Membered Oxa‐ and Aza‐Heterocycles via a Formal [4+1] Cyclization
av: Fengyan Gu, et al.
Publicerad: (2024-10-01)

Synthesis of highly substituted benzo-fused nitrogen heterocycles via tandem benzannulation/cyclization strategies
av: Willumstad, Thomas P. (Thomas Paul)
Publicerad: (2014)

Tandem benzannulation-ring closing metathesis strategy for the synthesis of benzo-fused nitrogen heterocycles ;
av: Mak, Xiao Yin
Publicerad: (2009)

Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles
av: Dai, Xi-Jie, et al.
Publicerad: (2020)

Oxidative Radical Cyclization–Cyclization Reaction Leading to 1H-Benzo[f]isoindole Derivatives
av: Eito Yoshioka, et al.
Publicerad: (2017-02-01)

DIRECTED ORTHO DILITHIATION OF DIARYL COMPOUNDS: FACILE SYNTHESIS OF TRICYCLIC COMPOUNDS BASED ON HETEROCYCLES FUSED TO TWO BENZENE RINGS
av: Chopra, Anu, et al.
Publicerad: (1997-12-01)

Oxidative radical ring-opening/cyclization of cyclopropane derivatives
av: Yu Liu, et al.
Publicerad: (2019-01-01)

Radical cyclization in heterocycle synthesis. Part 14. A simple and effective preparation of cyclic oxime ethers by photochemical radical addition–cyclization of acyclic oxime ethers
av: Okiko Miyata, et al.
Publicerad: (2003-09-01)

Flexible Enantioselectivity of Tryptophanase Attributable to Benzene Ring in Heterocyclic Moiety of D-Tryptophan
av: Akihiko Shimada, et al.
Publicerad: (2012-05-01)

Pyrene-containing twistarene : twelve benzene rings fused in a row
av: Chen, Wangqiao, et al.
Publicerad: (2020)

Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings
av: Ivan P. Mosiagin, et al.
Publicerad: (2021-06-01)

Tandem diazotization/cyclization approach for the synthesis of a fused 1,2,3-triazinone-furazan/furoxan heterocyclic system
av: Yuri A. Sidunets, et al.
Publicerad: (2024-09-01)

Visible-light-induced radical cascade cyclization: a catalyst-free synthetic approach to trifluoromethylated heterocycles
av: Chuan Yang, et al.
Publicerad: (2024-01-01)

Bu3SnH-mediated cyclopropyl radical cyclizations onto indole-3-carbaldehyde
av: Karen Fahey, et al.
Publicerad: (2013-06-01)

Oxidative or metal-mediated cyclization approaches to carbocycles and heterocycles
av: He, Xinyao
Publicerad: (2015)

Synthesis of new seven membered heterocyclic rings: An easy access to indeno-benzo[1,4]diazepines
av: Raza M. Ghalib, et al.
Publicerad: (2020-10-01)

Synthesis of bicyclo[3.3.1]nonane derivatives containing fused heterocyclic rings
av: L. Labanauskas, et al.
Publicerad: (2008-09-01)

One-Pot Synthesis of Aminated Benzo-Fused Heterocycles and N‑Substituted Dibenzothiophenes via Copper-Catalyzed Ullmann Type Reaction
av: Sawsan H. Alelaiwi, et al.
Publicerad: (2021-02-01)

Synthesis of fused tricyclic amines unsubstituted at the ring-junction positions by a cascade condensation, cyclization, cycloaddition then decarbonylation strategy
av: Iain Coldham, et al.
Publicerad: (2012-01-01)

Asymmetric synthesis of heterocycles via cation-directed cyclizations and rearrangements
av: Lamb, A, et al.
Publicerad: (2014)

Halogen-Induced Controllable Cyclizations as Diverse Heterocycle Synthetic Strategy
av: Hideyasu China, et al.
Publicerad: (2020-12-01)

Synthesis of Some Heterocyclic Compounds Via Cyclization of Imidoyl Chloride
av: G. T. Sedeek
Publicerad: (2013-10-01)

Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
av: Mathieu Morin, et al.
Publicerad: (2013-11-01)

Cr(II)-promoted internal cyclization of acyclic enediynes fused to benzo[b]thiophene core: Macrocycles versus 2-methylenecycloalkan-1-ols formation
av: A.E. Kulyashova, et al.
Publicerad: (2019-02-01)

Synthesis of fused N-heterocycles utilizing the heterocyclic enamine protocol
av: Yong Liu, et al.
Publicerad: (2003-05-01)

The Antitubercular Activities of Natural Products with Fused-Nitrogen-Containing Heterocycles
av: Helena I. Boshoff, et al.
Publicerad: (2024-02-01)

AN EFFICIENT MEDIUM-RING CYCLIZATION APPROACH TO THE GERMACRANES
av: Hodgson, D, et al.
Publicerad: (1995)

Synthesis of the Benzo-fused Indolizidine Alkaloid Mimics
av: Daniel L. Comins, et al.
Publicerad: (2007-11-01)

Selective alkylation of aminophenols
av: Jiaxi Xu, et al.
Publicerad: (2010-07-01)

Self-Terminating, Oxidative Radical Cyclizations
av: Uta Wille, et al.
Publicerad: (2004-05-01)

Use of the cascade α-oxo-amidoalkylation/transposition/ p-cationic cyclization of N-acyliminium ions in the synthesis of novel fused heterocyclic N,O-acetals
av: Adam Daïch, et al.
Publicerad: (2010-03-01)

Synthesis of Medium-Sized Heterocycles by Transition-Metal-Catalyzed Intramolecular Cyclization
av: Mickael Choury, et al.
Publicerad: (2020-07-01)

Recent advances in visible-light photoredox-catalyzed nitrogen radical cyclization
av: Pengzi Wang, et al.
Publicerad: (2020-06-01)

Target-Based 6-5 Fused Ring Heterocyclic Scaffolds Display Broad Antiparasitic Potency In Vitro
av: Darline Dize, et al.
Publicerad: (2024-02-01)