Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: formation of benzo-fused nitrogen heterocycles.

p-Iodophenol and its O-MOM-protected ether can be converted into iodoamines 2. These give cross-conjugated ketones 3 on oxidation with hypervalent iodides in the presence of methanol, and the ketones undergo radical cyclization. Exposure of the products to acid or sequential treatment with a Grignar...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Fletcher, S, Clive, D, Peng, J, Wingert, D
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2005