Centrosomes: Central no more?

Centrosomes: Central no more?

It has recently been found that the zygotic development of a morphologically normal fly can occur without properly functioning mitotic centrosomes. Does this mean that centrosomes are not required for cell division in animals at all?

Manylion Llyfryddiaeth
Prif Awdur:	Raff, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2001

Eitemau Tebyg

Centrosomes and microtubules: wedded with a ring.
gan: Raff, J
Cyhoeddwyd: (1996)

Centrosomes and cancer: lessons from a TACC.
gan: Raff, J
Cyhoeddwyd: (2002)

Phase separation and the centrosome: a fait accompli?
gan: Raff, J
Cyhoeddwyd: (2019)

Centrioles, centrosomes, and cilia in health and disease.
gan: Nigg, E, et al.
Cyhoeddwyd: (2009)

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
gan: Barros, T, et al.
Cyhoeddwyd: (2005)

Centrosome amplification and cancer: A question of sufficiency.
gan: Raff, J, et al.
Cyhoeddwyd: (2017)

Centrosome function and assembly in animal cells
gan: Conduit, P, et al.
Cyhoeddwyd: (2015)

The central role of the centrosome
gan: Isabel Stötzel, et al.
Cyhoeddwyd: (2022-12-01)

The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.
gan: Conduit, P, et al.
Cyhoeddwyd: (2014)

Different Drosophila cell types exhibit differences in mitotic centrosome assembly dynamics.
gan: Conduit, P, et al.
Cyhoeddwyd: (2015)

Centrosome amplification can initiate tumorigenesis in flies.
gan: Basto, R, et al.
Cyhoeddwyd: (2008)

Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila.
gan: Baumbach, J, et al.
Cyhoeddwyd: (2012)

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts.
gan: Conduit, P, et al.
Cyhoeddwyd: (2010)

LK6, a short lived protein kinase in Drosophila that can associate with microtubules and centrosomes.
gan: Kidd, D, et al.
Cyhoeddwyd: (1997)

Structural basis for mitotic centrosome assembly in flies
gan: Feng, Z, et al.
Cyhoeddwyd: (2017)

Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos.
gan: Wakefield, J, et al.
Cyhoeddwyd: (2000)

Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour
gan: Lee, M, et al.
Cyhoeddwyd: (2001)

LK6, a novel Drosophila protein kinase that is rapidly turned over and is associated with microtubules and centrosomes.
gan: Kidd, D, et al.
Cyhoeddwyd: (1996)

Centrioles regulate centrosome size by controlling the rate of Cnn incorporation into the PCM.
gan: Conduit, P, et al.
Cyhoeddwyd: (2010)

A positive feedback loop drives centrosome maturation in flies
gan: Alvarez Rodrigo, I, et al.
Cyhoeddwyd: (2018)

Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila
gan: Janina Baumbach, et al.
Cyhoeddwyd: (2012-08-01)

The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.
gan: Gergely, F, et al.
Cyhoeddwyd: (2000)

The centrosomal protein CP190 regulates myosin function during early Drosophila development.
gan: Chodagam, S, et al.
Cyhoeddwyd: (2005)

Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour.
gan: Lee, M, et al.
Cyhoeddwyd: (2001)

A molecular mechanism of mitotic centrosome assembly in Drosophila
gan: Conduit, PT, et al.
Cyhoeddwyd: (2014)

Studying centrosome formation and the consequences of centrosome loss in Drosophila melanogaster
gan: Baumbach, J
Cyhoeddwyd: (2014)

The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division.
gan: Butcher, R, et al.
Cyhoeddwyd: (2004)

Drosophila Ana1 is required for centrosome assembly and centriole elongation
gan: Saurya, S, et al.
Cyhoeddwyd: (2016)

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila
gan: Dobbelaere, J, et al.
Cyhoeddwyd: (2008)

Cdk1 phosphorylates Drosophila Sas-4 to recruit Polo to daughter centrioles and convert them to centrosomes
gan: Raff, J, et al.
Cyhoeddwyd: (2016)

Choreography of the centrosome
gan: Maria Alvarado-Kristensson
Cyhoeddwyd: (2020-01-01)

D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo.
gan: Gergely, F, et al.
Cyhoeddwyd: (2000)

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.
gan: Jeroen Dobbelaere, et al.
Cyhoeddwyd: (2008-09-01)

A molecular mechanism of mitotic centrosome assembly in Drosophila
gan: Paul T Conduit, et al.
Cyhoeddwyd: (2014-08-01)

Evidence that a positive feedback loop drives centrosome maturation in fly embryos
gan: Alvarez-Rodrigo, I, et al.
Cyhoeddwyd: (2019)

Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster
gan: Marisa M. L. Tillery, et al.
Cyhoeddwyd: (2018-08-01)

The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.
gan: Marko Panic, et al.
Cyhoeddwyd: (2015-05-01)

LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion
gan: Runsheng He, et al.
Cyhoeddwyd: (2013-09-01)

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.
gan: Giet, R, et al.
Cyhoeddwyd: (2002)

The Centrosome: Conclusions and Perspectives
gan: Rustem E. Uzbekov, et al.
Cyhoeddwyd: (2022-12-01)