Antigen discrimination in primary human T cells

Antigen discrimination in primary human T cells

<p>Antigen discrimination is the process by which T cells differentiate self from foreign antigens. They do this using their T cell receptors (TCRs) that recognize peptide antigens bound to major histocompatibility complexes (pMHCs) and this TCR/pMHC interaction is augmented by a host of other...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Pettmann, J
Awduron Eraill:	Davis, S
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2021
Pynciau:	Experimental immunology

Eitemau Tebyg

Identifying signalling molecules controlling T cell antigen sensitivity and discrimination
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Cyhoeddwyd: (2022)

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The critical role of IL-23 receptor positive T cells in the pathogenesis of anterior uveitis associated with spondyloarthropathy
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The role of serine metabolism in B lymphocytes
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Cyhoeddwyd: (2022)

Developing viral vectored vaccines for MAGE-expressing tumours
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Developing recombinant overlapping peptides of prostate-specific antigen as vaccine
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Cyhoeddwyd: (2022)

B cell responses to protein adducts
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Cyhoeddwyd: (2023)

Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis
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Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies against self-antigens
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Cyhoeddwyd: (2023-11-01)

Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer
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Cyhoeddwyd: (2023)

Distinct populations of antigen-specific tissue-resident CD8+ T cells in human cervix mucosa
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Cyhoeddwyd: (2021-08-01)

Apoptotic Cells Deliver Processed Antigen to Dendritic Cells for Cross-Presentation
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Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity
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Proteogenomic identification of an immunogenic antigen derived from human endogenous retrovirus in renal cell carcinoma
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Cyhoeddwyd: (2023-08-01)

THE SCHISTOSOMULA TEGUMENT ANTIGEN AS A POTENTIAL CANDIDATE FOR THE EARLY SEROLOGICAL DIAGNOSIS OF SCHISTOSOMIASIS MANSONI
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Cyhoeddwyd: (2013-04-01)

Experimental study of sources of noise from heavy earth-moving machinery/
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A quantitative analysis of the contribution of costimulation to T cell activation by the T cell receptor and chimeric antigen receptors
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Cyhoeddwyd: (2023)

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
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Cyhoeddwyd: (2023-05-01)

SARS-CoV-2 antigen-carrying extracellular vesicles activate T cell responses in a human immunogenicity model
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Cyhoeddwyd: (2024-01-01)

Adaptive discrimination between harmful and harmless antigens in the immune system by predictive coding
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Cyhoeddwyd: (2023-01-01)

Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer
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Cyhoeddwyd: (2022-04-01)

The role of CD2 in recognition of weak antigens and its implications for adoptive cell transfer
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Cyhoeddwyd: (2021)

Characterising novel vaccine adjuvants in eliciting antigen-specific CD8+ T cell immunity
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Cyhoeddwyd: (2023)

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine
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Cyhoeddwyd: (2023-01-01)

Th2-skewed T cells correlate with B cell response to α-Gal and tick antigens in α-Gal syndrome
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Cyhoeddwyd: (2023-03-01)

Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
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Cyhoeddwyd: (2021-10-01)

Potential effects of Linh Loc Son hard capsule – a Vietnamese herbal combination in immunodeficiency induced by cyclophosphamide on mice
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Cyhoeddwyd: (2024-09-01)

mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming
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Cyhoeddwyd: (2022-07-01)

Imaging and analysis on the interaction between human antigen-pulsed Vδ2 T cells and antigen-specific CD4 T cells
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Cyhoeddwyd: (2021-06-01)

Monkeypox infection elicits strong antibody and B cell response against A35R and H3L antigens
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Cyhoeddwyd: (2023-02-01)

Protocol for generation of human peptide-specific primary CD8+ T cell lines
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Cyhoeddwyd: (2022-09-01)

Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy
gan: M. Hope Robinson, et al.
Cyhoeddwyd: (2023-08-01)

Investigation of HLA-E intracellular transport and antigen presentation
gan: He, W
Cyhoeddwyd: (2023)

NK cells contribute to reovirus-induced IFN responses and loss of tolerance to dietary antigen
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Cyhoeddwyd: (2022-08-01)

Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals
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Cyhoeddwyd: (2021-07-01)

T cell receptor sequences are the dominant factor contributing to the phenotype of CD8+ T cells with specificities against immunogenic viral antigens
gan: Daniel G. Chen, et al.
Cyhoeddwyd: (2023-11-01)

A nerve-goblet cell association promotes allergic conjunctivitis through rapid antigen passage
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Cyhoeddwyd: (2023-11-01)

Design of diversified chimeric antigen receptors through rational module recombination
gan: Wen Si, et al.
Cyhoeddwyd: (2023-04-01)

Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis
gan: Molly T. Radosevich, et al.
Cyhoeddwyd: (2023-12-01)