Exploring tumour suppressor ATRX and telomere maintenance in MLLr leukaemia

<p>The acquisition of limitless replicative potential, is crucial for cancer development. Normally, cells undergo senescence once the telomeres (sequences that protect genes from being lost after replication due to the end replication problem), reach a critically short length. In cancer, two m...

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Bibliographic Details
Main Author: Gracias, D
Other Authors: Clynes, D
Format: Thesis
Published: 2018