Engineering of a polydisperse small heat-shock protein reveals conserved motifs of oligomer plasticity
Small heat-shock proteins (sHSPs) are molecular chaperones that bind partially and globally unfolded states of their client proteins. Previously, we discovered that the archaeal Hsp16.5, which forms ordered and symmetric 24-subunit oligomers, can be engineered to transition to an ordered and symmetr...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Published: |
Elsevier
2018
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