Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele.

We tested the hypothesis that a single allele deletion of neuronal nitric oxide synthase (nNOS) would impair the neural control of heart rate following physical training, and that this phenotype could be restored following targeted gene transfer of nNOS. Voluntary wheel-running (+EX) in heterozygous...

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Bibliographic Details
Main Authors: Danson, E, Mankia, K, Golding, S, Dawson, T, Everatt, L, Cai, S, Channon, K, Paterson, D
Format: Journal article
Language:English
Published: 2004