Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele.
We tested the hypothesis that a single allele deletion of neuronal nitric oxide synthase (nNOS) would impair the neural control of heart rate following physical training, and that this phenotype could be restored following targeted gene transfer of nNOS. Voluntary wheel-running (+EX) in heterozygous...
المؤلفون الرئيسيون: | Danson, E, Mankia, K, Golding, S, Dawson, T, Everatt, L, Cai, S, Channon, K, Paterson, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2004
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مواد مشابهة
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Impaired regulation of neuronal nitric oxide synthase during exercise abolishes training-induced facilitation of cardiac vagal function in mice lacking one nNOS allele
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Targeted nNOS gene transfer into the cardiac vagus rapidly increases parasympathetic function in the pig.
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