The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription.

Up-regulation of utrophin gene expression is recognized as a plausible therapeutic approach in the treatment of Duchenne muscular dystrophy (DMD). We have designed and engineered new zinc finger-based transcription factors capable of binding and activating transcription from the promoter of the dyst...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Corbi, N, Libri, V, Fanciulli, M, Tinsley, J, Davies, K, Passananti, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2000