Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity.

The major heat-inducible Hsp70 is a potent survival protein that confers cytoprotection against numerous death-inducing stimuli and increases the tumorigenicity of rodent cells. The depletion of Hsp70 by adenovirus-mediated transfer of antisense cDNA induces caspase-independent death of tumorigenic...

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Bibliográfalaš dieđut
Váldodahkkit: Gyrd-Hansen, M, Nylandsted, J, Jäättelä, M
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2004