Stereoselective synthesis of cyclohexanes via an iridium catalyzed (5 + 1) annulation strategy
An iridium catalyzed method for the synthesis of functionalized cyclohexanes from methyl ketones and 1,5-diols is described. This process operates by two sequential hydrogen borrowing reactions, providing direct access to multisubstituted cyclic products with high levels of stereocontrol. This metho...
Main Authors: | , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2018
|