Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...
Autori principali: | Liu, Y, Hu, Z, Cheng, J, Siejka-Zielinska, P, Chen, J, Inoue, M, Ahmed, A, Song, C |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Springer Nature
2021
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