Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...

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Detalhes bibliográficos
Main Authors: Liu, Y, Hu, Z, Cheng, J, Siejka-Zielinska, P, Chen, J, Inoue, M, Ahmed, A, Song, C
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2021