Structural and functional studies of perforin-like proteins implicated in zoonotic parasitic diseases
<p>MACPF/CDCs are an ancient superfamily of pore forming proteins that have evolved a critical role in both cellular defence and attack. Many copies of MACPF/CDC proteins are released by a cell before binding to target membranes, oligomerising and undergoing a large structural rearrangement to...
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| Format: | Thesis |
| Language: | English |
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2019
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