Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

The perforated patch whole-cell configuration of the patch-clamp technique was applied to superficial glucagon-secreting alpha-cells in intact mouse pancreatic islets. alpha-cells were distinguished from the beta- and delta-cells by the presence of a large TTX-blockable Na+ current, a TEA-resistant...

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Bibliographic Details
Main Authors: Göpel, S, Kanno, T, Barg, S, Weng, X, Gromada, J, Rorsman, P
Format: Journal article
Language:English
Published: 2000