Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma

Purpose: Pancreatic stellate cells (PSC) drive desmoplasia in pancreatic cancer. Our study analyzed both tumor and PSC, since interaction of these cell types may promote tumor progression. Results: SPARC was expressed predominantly in the peritumoral and distal stroma. SPARC in distal stroma correla...

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Bibliographic Details
Main Authors: Mantoni, T, Schendel, R, Rödel, F, Niedobitek, G, Al-Assar, O, Masamune, A, Brunner, T
Format: Journal article
Language:English
Published: 2008