Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies.
A bioanalytical method for the analysis of artesunate (ARS) and its metabolite dihydroartemisinin (DHA) in human plasma using protein precipitation and liquid chromatography coupled to positive tandem mass spectroscopy was developed. The method was validated according to published US FDA-guidelines...
المؤلفون الرئيسيون: | Lindegardh, N, Hanpithakpong, W, Kamanikom, B, Singhasivanon, P, Socheat, D, Yi, P, Dondorp, A, Mcgready, R, Nosten, F, White, N, Day, N |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2008
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مواد مشابهة
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Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge.
حسب: Lindegardh, N, وآخرون
منشور في: (2011) -
A liquid chromatographic-tandem mass spectrometric method for determination of artesunate and its metabolite dihydroartemisinin in human plasma.
حسب: Hanpithakpong, W, وآخرون
منشور في: (2008) -
A liquid chromatographic-tandem mass spectrometric method for determination of artemether and its metabolite dihydroartemisinin in human plasma.
حسب: Hanpithakpong, W, وآخرون
منشور في: (2009) -
Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC-MS/MS.
حسب: Lindegardh, N, وآخرون
منشور في: (2011) -
Artemisinin resistance in Plasmodium falciparum malaria.
حسب: Dondorp, A, وآخرون
منشور في: (2009)