Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies.

Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies.

A bioanalytical method for the analysis of artesunate (ARS) and its metabolite dihydroartemisinin (DHA) in human plasma using protein precipitation and liquid chromatography coupled to positive tandem mass spectroscopy was developed. The method was validated according to published US FDA-guidelines...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Lindegardh, N, Hanpithakpong, W, Kamanikom, B, Singhasivanon, P, Socheat, D, Yi, P, Dondorp, A, Mcgready, R, Nosten, F, White, N, Day, N
Materialtyp:	Journal article
Språk:	English
Publicerad:	2008

Liknande verk

Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge.
av: Lindegardh, N, et al.
Publicerad: (2011)

A liquid chromatographic-tandem mass spectrometric method for determination of artesunate and its metabolite dihydroartemisinin in human plasma.
av: Hanpithakpong, W, et al.
Publicerad: (2008)

A liquid chromatographic-tandem mass spectrometric method for determination of artemether and its metabolite dihydroartemisinin in human plasma.
av: Hanpithakpong, W, et al.
Publicerad: (2009)

Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC-MS/MS.
av: Lindegardh, N, et al.
Publicerad: (2011)

Artemisinin resistance in Plasmodium falciparum malaria.
av: Dondorp, A, et al.
Publicerad: (2009)

Intrahost modeling of artemisinin resistance in Plasmodium falciparum
av: Saralamba, S, et al.
Publicerad: (2010)

Intrahost modeling of artemisinin resistance in Plasmodium falciparum.
av: Saralamba, S, et al.
Publicerad: (2011)

Quantification of artemisinin in human plasma using liquid chromatography coupled to tandem mass spectrometry.
av: Lindegardh, N, et al.
Publicerad: (2009)

Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of oseltamivir and its metabolite oseltamivir carboxylate in plasma, saliva and urine.
av: Lindegårdh, N, et al.
Publicerad: (2007)

Artemisinin Resistance in Plasmodium falciparum Malaria (vol 361, pg 455, 2009)
av: Dondorp, A, et al.
Publicerad: (2009)

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
av: Das, D, et al.
Publicerad: (2013)

Artemisinin resistance: current status and scenarios for containment.
av: Dondorp, A, et al.
Publicerad: (2010)

Intrarectal artemisinin derivatives.
av: Nosten, F, et al.
Publicerad: (1998)

Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study
av: Phyo, A, et al.
Publicerad: (2012)

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study.
av: Phyo, A, et al.
Publicerad: (2012)

Laboratory detection of artemisinin-resistant Plasmodium falciparum.
av: Chotivanich, K, et al.
Publicerad: (2014)

Development and validation of a high-throughput zwitterionic hydrophilic interaction liquid chromatography solid-phase extraction-liquid chromatography-tandem mass spectrometry method for determination of the anti-influenza drug peramivir in plasma.
av: Lindegardh, N, et al.
Publicerad: (2008)

Artemisinin Resistance in Plasmodium falciparum Malaria REPLY
av: Dondorp, A, et al.
Publicerad: (2009)

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study
av: Phyo, A, et al.
Publicerad: (2012)

Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria.
av: Tarning, J, et al.
Publicerad: (2009)

Use of artemisinin derivatives for the control of malaria.
av: Nosten, F, et al.
Publicerad: (1998)

Artemisinin derivatives in the treatment of falciparum malaria in pregnancy.
av: Mcgready, R, et al.
Publicerad: (1998)

Validation and application of a liquid chromatographic-mass spectrometric method for determination of artesunate in pharmaceutical samples.
av: Lindegårdh, N, et al.
Publicerad: (2007)

Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.
av: Teja-Isavadharm, P, et al.
Publicerad: (2004)

Artemisinin resistance: current status and scenarios for containment (vol 8, pg 272, 2010)
av: Dondorp, A, et al.
Publicerad: (2010)

Population pharmacokinetic and pharmacodynamic modeling of artemisinin resistance in Southeast Asia
av: Lohy Das, J, et al.
Publicerad: (2017)

A major genome region underlying artemisinin resistance in malaria.
av: Cheeseman, I, et al.
Publicerad: (2012)

Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum.
av: Imwong, M, et al.
Publicerad: (2010)

A major genome region underlying artemisinin resistance in malaria.
av: Cheeseman, I, et al.
Publicerad: (2012)

Studies of the neurotoxicity of oral artemisinin derivatives in mice.
av: Nontprasert, A, et al.
Publicerad: (2000)

Pitfalls in estimating piperaquine elimination.
av: Tarning, J, et al.
Publicerad: (2005)

Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.
av: Maude, R, et al.
Publicerad: (2012)

Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases.
av: Lindegardh, N, et al.
Publicerad: (2006)

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria.
av: Ashley, E, et al.
Publicerad: (2010)

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.
av: Mok, S, et al.
Publicerad: (2011)

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria.
av: Tarning, J, et al.
Publicerad: (2012)

Neuropathologic toxicity of artemisinin derivatives in a mouse model.
av: Nontprasert, A, et al.
Publicerad: (2002)

Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice.
av: Nontprasert, A, et al.
Publicerad: (1998)

Effects of artemisinin derivatives on malaria transmissibility.
av: Price, R, et al.
Publicerad: (1996)

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria
av: Ashley, E, et al.
Publicerad: (2010)