IL-15 promotes polyfunctional NK cell responses to influenza by boosting IL-12 production
IL-15 is a key regulator of NK cell maintenance and proliferation and synergizes with other myeloid cell–derived cytokines to enhance NK cell effector function. At low concentrations, trans-presentation of IL-15 by dendritic cells can activate NK cells, whereas at higher concentrations it can act di...
Main Authors: | , , , |
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Format: | Journal article |
Published: |
American Association of Immunologists
2018
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