IL-15 promotes polyfunctional NK cell responses to influenza by boosting IL-12 production
IL-15 is a key regulator of NK cell maintenance and proliferation and synergizes with other myeloid cell–derived cytokines to enhance NK cell effector function. At low concentrations, trans-presentation of IL-15 by dendritic cells can activate NK cells, whereas at higher concentrations it can act di...
主要な著者: | , , , |
---|---|
フォーマット: | Journal article |
出版事項: |
American Association of Immunologists
2018
|