IL-15 promotes polyfunctional NK cell responses to influenza by boosting IL-12 production

IL-15 promotes polyfunctional NK cell responses to influenza by boosting IL-12 production

IL-15 is a key regulator of NK cell maintenance and proliferation and synergizes with other myeloid cell–derived cytokines to enhance NK cell effector function. At low concentrations, trans-presentation of IL-15 by dendritic cells can activate NK cells, whereas at higher concentrations it can act di...

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Bibliographic Details
Main Authors:	Wagstaffe, HR, Nielsen, CM, Riley, EM, Goodier, MR
Format:	Journal article
Published:	American Association of Immunologists 2018

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