Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.

Metastasis is a frequent and lethal complication of cancer. Vascular endothelial growth factor-C (VEGF-C) is a recently described lymphangiogenic factor. Increased expression of VEGF-C in primary tumours correlates with dissemination of tumour cells to regional lymph nodes. However, a direct role fo...

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Bibliographic Details
Main Authors: Mandriota, S, Jussila, L, Jeltsch, M, Compagni, A, Baetens, D, Prevo, R, Banerji, S, Huarte, J, Montesano, R, Jackson, D, Orci, L, Alitalo, K, Christofori, G, Pepper, MS
Format: Journal article
Language:English
Published: 2001

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