Regional specialization of macrophages along the gastrointestinal tract

The tissue microenvironment is a major driver in imprinting tissue-specific macrophage functions in various mammalian tissues. As monocytes are recruited into the gastrointestinal (GI) tract at steady state and inflammation, they rapidly adopt a tissue-specific and distinct transcriptome. However, t...

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Bibliographic Details
Main Authors: Berthold, DL, Jones, KDJ, Udalova, IA
Format: Journal article
Language:English
Published: Cell Press 2021