Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity

Regulatory enhancer elements in solid tumours remain poorly characterized. Here we apply micro-scale chromatin profiling to survey the distal enhancer landscape of primary gastric adenocarcinoma (GC), a leading cause of global cancer mortality. Integrating 110 epigenomic profiles from primary GCs, n...

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Bibliographic Details
Main Authors: Ooi, W, Xing, M, Xu, C, Yao, X, Ramlee, M, Lim, M, Cao, F, Lim, K, Babu, D, Poon, L, Lin Suling, J, Qamra, A, Irwanto, A, Qu Zhengzhong, J, Nandi, T, Lee-Lim, A, Chan, Y, Tay, S, Lee, M, Davies, J, Wong, W, Soo, K, Chan, W, Ong, H, Chow, P, Wong, C, Rha, S, Liu, J, Hillmer, A, Hughes, J, Rozen, S, Teh, B, Fullwood, M, Li, S, Tan, P
Format: Journal article
Language:English
Published: Springer Nature 2016