HIV entry in macrophages is dependent on intact lipid rafts.

Macrophages are an important natural target cell for HIV-1, but previous studies of virus entry into these cells are limited, and the involvement of membrane cholesterol and lipid rafts is unknown. Cholesterol disruption of macrophage membranes using four pharmacological agents acting by different m...

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Bibliographic Details
Main Authors: Carter, G, Bernstone, L, Sangani, D, Bee, J, Harder, T, James, W
Format: Journal article
Language:English
Published: 2009