Stereoselective synthesis of pyrrolidines: catalytic oxidative cyclizations mediated by osmium.

(Chemical Equation Presented) A new pathway for oxidative cyclization : N-protected α-amino alcohols with distal alkene units cyclize with complete stereoselectivity and stereospecificity to cispyrrolidines, dependent on the substitution pattern of the starting material. In addition to providing nit...

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Bibliographic Details
Main Authors: Donohoe, T, Churchill, G, Wheelhouse, K, Glossop, P
Format: Journal article
Language:English
Published: 2006