EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method

<p>Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively). Conversely, treatment with C2C12 myotube...

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Hlavní autoři: Hanson, B, Vorobieva, I, Zheng, W, Conceição, M, Lomonosova, Y, Mäger, I, Puri, PL, El Andaloussi, S, Wood, MJA, Roberts, TC
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2023