EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method

<p>Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively). Conversely, treatment with C2C12 myotube...

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Bibliographic Details
Main Authors: Hanson, B, Vorobieva, I, Zheng, W, Conceição, M, Lomonosova, Y, Mäger, I, Puri, PL, El Andaloussi, S, Wood, MJA, Roberts, TC
Format: Journal article
Language:English
Published: Cell Press 2023

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