Ligand recognition mechanism of thiamine pyrophosphate riboswitch aptamer
Riboswitches regulate gene expression by coupling ligand binding to a structural transition of the riboswitch, but the coupling mechanism is still controversial. We addressed this issue by characterizing both the ligand-free state of the Escherichia coli thiamine pyrophosphate (TPP) riboswitch aptam...
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Formáid: | Journal article |
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Korean Chemical Society
2017
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