Ligand recognition mechanism of thiamine pyrophosphate riboswitch aptamer

Riboswitches regulate gene expression by coupling ligand binding to a structural transition of the riboswitch, but the coupling mechanism is still controversial. We addressed this issue by characterizing both the ligand-free state of the Escherichia coli thiamine pyrophosphate (TPP) riboswitch aptam...

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Príomhchruthaitheoirí: Uhm, H, Hohng, S
Formáid: Journal article
Foilsithe / Cruthaithe: Korean Chemical Society 2017