A comparison of the binding sites of antibodies and single-domain antibodies

Antibodies are the largest class of biotherapeutics. However, in recent years, single-domain antibodies have gained traction due to their smaller size and comparable binding affinity. Antibodies (Abs) and single-domain antibodies (sdAbs) differ in the structures of their binding sites: most signific...

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Bibliographic Details
Main Authors: Gordon, GL, Capel, HL, Guloglu, B, Richardson, E, Stafford, RL, Deane, CM
Format: Journal article
Language:English
Published: Frontiers Media 2023