Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice.

We have investigated the transcriptional regulation of the human embryonic zeta-globin gene promoter. First, we examined the effect that deletion of sequences 5' to zeta-globin's CCAAT box have on zeta-promoter activity in erythroid cell lines. Deletions of sequences between -116 and -556...

Description complète

Détails bibliographiques
Auteurs principaux: Pondel, MD, Sharpe, J, Clark, S, Pearson, L, Wood, W, Proudfoot, N
Format: Journal article
Langue:English
Publié: 1996