Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice.

We have investigated the transcriptional regulation of the human embryonic zeta-globin gene promoter. First, we examined the effect that deletion of sequences 5' to zeta-globin's CCAAT box have on zeta-promoter activity in erythroid cell lines. Deletions of sequences between -116 and -556...

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Hlavní autoři: Pondel, MD, Sharpe, J, Clark, S, Pearson, L, Wood, W, Proudfoot, N
Médium: Journal article
Jazyk:English
Vydáno: 1996