3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation

<br><strong>Background<br></strong> Triple negative breast cancer (TNBC) poses a serious clinical challenge as it is an aggressive form of the disease that lacks estrogen receptor, progesterone receptor, and ERBB2 (formerly HER2) gene amplification, which limits the treatment...

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Bibliographic Details
Main Authors: Skaripa-Koukelli, I, Hauton, D, Walsby-Tickle, J, Thomas, E, Owen, J, Lakshminarayanan, A, Able, S, McCullagh, J, Carlisle, R, Vallis, K
Format: Journal article
Language:English
Published: BioMed Central 2021