Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines
Diphtheria toxin mutant CRM197 is a common carrier protein for glycoconjugate vaccines, which has been proven an effective protein vector for, among others, meningococcal carbohydrates. The wide-range use of this protein in massive vaccine production requires constant increase of production yields a...
Main Authors: | Pecetta, S, Vijayakrishnan, B, Romano, M, Proietti, D, Surdo, P, Balocchi, C, Mori, E, Davis, B, Berti, F |
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格式: | Journal article |
语言: | English |
出版: |
Elsevier
2016
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