The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

BACKGROUND: Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing prostate cancer. The promoter location of the risk allele, and its ability to...

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Detalhes bibliográficos
Main Authors:	Whitaker, H, Kote-Jarai, Z, Ross-Adams, H, Warren, A, Burge, J, George, A, Bancroft, E, Jhavar, S, Leongamornlert, D, Tymrakiewicz, M, Saunders, E, Page, E, Mitra, A, Mitchell, G, Lindeman, G, Evans, D, Blanco, I, Mercer, C, Rubinstein, W, Clowes, V, Douglas, F, Hodgson, S, Walker, L, Donaldson, A, Izatt, L, Dorkins, H, Male, A, Tucker, K, Stapleton, A, Lam, J, Kirk, J, Lilja, H, Easton, D, Cooper, C, Eeles, R, Neal, D
Formato:	Journal article
Idioma:	English
Publicado em:	Public Library of Science 2010

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

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